His little sister Nezuko is the only survivor, but she has been transformed into a demon herself! Tanjiro sets out on a dangerous journey to find a way to return his sister to normal and destroy the demon who ruined his life.

After centuries of preparation and training, the Demon Slayer Corps has come face-to-face with their nemesis, Muzan Kibutsuji. It is a desperate battle and several Demon Slayers have already been killed. Tanjiro himself has engaged Muzan, and, despite giving it everything he has, is taken out of the fight! Although severely injured and near death, he sees a vision of his ancestor that may hold the key to finally destroying Muzan! Can Tanjiro recover enough strength to fight Muzan to the finish?