After an undersea tangle with mermaids and fish-men, Portgaz D. Ace leads his Spade Pirates crew to the New World, a place where pirate masters and rookies battle for territory and treasure.

As he flees memories of his secret past, Ace seeks pirating infamy so powerful it will change the world order. To achieve this goal, he sets his sights on one of the strongest fleets in the ocean—the Whitebeard Pirates, ruled over by dread pirate Whitebeard, the strongest man in the world!